Take I-81 South to I -40 East to Exit 435 (Newport) and follow Hwy 321 South all the way into Gatlinburg. Approximate drive time from interstate: 45 minutes
FROM LEXINGTON:
From Knoxville take I-75 North and follow Highway 321 to I-40 East to Exit 435 and follow Highway 321 South. Approximate drive time from interstate: 45 minutes.
FROM CHATTANOOGA:
Take Exit 81 on I-75 North and follow Highway 321 North to Gatlinburg through Maryville and Townsend. Approximate driving time from interstate: 1 hour 10 minutes.
FROM NASHVILLE:
Take I-75 South to Exit 81 and follow Highway 321 North through Maryville and Townsend to Gatlinburg. Approximate driving time from interstate: 1 hour 10 minutes.
FROM ASHEVILLE:
Take I-40 West to Exit 440 and follow Highway 321 South to Gatlinburg. Approximate drive time from interstate: 45 minutes.
FROM ATLANTA:
Take I-85 North to I-985 North to US 23. Take US 23 to Highway 23/441 to Highway 74/441 through Cherokee, North Carolina to Gatlinburg. Approximate driving time: 4 hours 10 minutes
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